Re: Handling new born kittens - what are the rules?
This is my opinion ...if you're unsure, it's best to ask a vet/vet-tech
If the mother is taking care of them, I would say the only handling you should do is after 2 or 3 weeks old (less fragile). Of course, you should be gentle since they're still pretty frail. Just hold them in your lap, or lay down and have them on your chest, and gently pet them.
If you're taking care of orphaned kittens, obviously you'll need to handle them to bottle feed and wipe their under-tail area for elimination.