So sorry to hear about your separation. I know this is a tough time for everyone. I went through this about 2 years ago. It will be tough for the first few months, but hang in there, time does heal all wounds, and you will be OK. The main thing is to take care of you. Mr. Tuffy will adapt to his new home and he will also be OK...don't worry. I also think he will welcome having you all to himself again, particularly when the emotional roller coaster takes off *hugz*
The tips catloverami posted are great.
Good luck to you and Mr. Tuffy!