My daughter's cat is an experienced traveler. Harper made the usual trips from colege to our house (200 miles each way) with no difficulty. I have an older cat and one of Harper's littermates - we just open the crate and Harper joins my girls.
Last summer, Harper and my daughter moved 1200 miles away. They made the trip in two days. Since then, they have flown back here twice. In two weeks, they will be moving 700 miles further away (my daughter's job means she moves often).
I would not fly a beloved pet in cargo of any plane, under any circumstances.
Skin kids - Jason, Kevin, Allison
Canine kids - Bennett & Bailey (always in our hearts), Riley, Banker, Rogue and Boz
Feline kids - Zoey, Talley and Abra