until you find a better solution, I would try to at least schedule her appointments for 1st thing in the morning as if she is going in for surgery or something - i.e. take all food away after 10 pm or something so that you have a better chance of there being nothing to poop out at least. she might still pee, but HOPEFULLY she will have emptied her bladder as well before the appointment.
Xanax worked great to reduce anxiety in one of my fosters, but not sure you'd want to do that before an appointment since I'm not sure if that would really mess up test results if you were getting blood or urine drawn.
and here's a really crazy idea - I had a foster who pooped and peed in his carrier 3 times while I had him and had to bring him back and forth for checkups. I finally just let him out of his carrier while I drove (put up a barrier, of course, so he couldn't disturb my actual driving) and provided him with a small little box in the back seat. he used it every time! no mess in the carrier! then i would just put him in the carrier again once I got to the shelter to carry him in. the drive to the shelter I volunteer for can be 1/2 an hour drive on a perfect day, and an hour during rush hour, so I had to come up with some kind of solution. this worked great!
I also do the whole "make the carrier a positive space" thing, too, though. I always leave it out and open for them to explore or even sit in if they want. I like to put treats in there as well in a puzzle feeder or something to make it more "fun" to explore.
do the 2 cats travel in the SAME carrier or separate ones? if they used to travel in the same big one before and had no problems, maybe you could consider that as well. I took care of a friend's cat for several months and the friend insisted the cat hated car travel, and was absolutely sure nothing would cure her of it. so, without telling her, I actually did start working on it and it seemed to be having some success, but I didn't have enough time really to see if it would make a difference in the long run - I would just bring the cat in the car for very very short stints to slowly get used to it. started out with her just exploring around the car in the garage on her own, then sat in the car in the garage with her for a couple minutes at a time. moved up to starting the car up and backing it out onto the driveway and sit there for a couple minutes. then added a short drive and parked for a few minutes, etc, etc, etc... no throw up or crazy screaming or yowling like she would do with her person. it seemed to be working...
I wish you luck!!!
Maggie & Phoebe
Kitty, Lucy Girl, Bobby Boy, and my sweet Angel forever in my heart.
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