I do not know if this will help, but this is the best solution I could find to help with my guy, is so much like a 'worm', and has so much strength! I am alone here, so I was stuck.
He was taking at one point, 5 meds a day for IBD. Now it is just 2.
This is what I do:
I put him behind me, on the left side of an armchair, body behind me, from chest to head in corner. I sit slightly turned, but trapping him in with my body. He cannot jump up, because he is restrained by my body. I get him against the back of the chair and the left solid arm. I put my left arm around him and open his mouth. He does struggle, but he is getting a bit better. Now I am telling him to "open" when I open his mouth. I slip the syringe in the corner of his mouth and squirt---not too hard or fast, just a quick gentle squeeze. Then I close his mouth, to make sure he swallows it. I also give him a chaser of some water..
I keep his mouth closed for a few seconds, to be sure he swallows all of it and does not spit it out or even drool it out.. The water helps with that.
I then take a napkin and wipe his face...making sure his mouth is closed.
In the beginning, he was horrible to medicate!
I found he would not swallow pills, even in gel caps! He would put them in the corner of his mouth, wait until I let him go. I would find them everywhere. Now he is much better. I also tell him to 'swallow'.
With the liquid, if he does not like the taste of it: some meds are impossible to make palatable ~~~ Artie will hold it in his mouth until I let him go.
I have found him, drooling it out all over the house!! It was really alarming the first time I saw drool hanging from both sides of his mouth!!!
Then I realized what it was from...Now I am wise to him..
I still have to sneak up on Artie for the meds. I try to do it when he is quiet and resting. Waking him while napping did not turn out well. He got very jittery of me, so I get him when he is resting or least expects it..
Hope this helps or gives you ideas...