Many viewers aren't aware of this, but Earl, Randy, and their buddies live in western Maryland. The characters often make references to real locations, and the show's creator went to college somewhere nearby.
Let's be honest -- the characters are pure white trash, and the show constantly makes fun of them. If the show weren't so hilarious, and if the characters hadn't been created with such comedic affection, there'd be plenty of people out there protesting the stereotypes.
Some of my favorite moments:
When Randy wanted to go to the state fair to see the world's tallest midget (the previous year, the state fair had featured the world's shortest giant...probably the same guy).
Joy and Darnell's liquor store bridal registry ("8 bottles of tequila...got it")
Earl, Jr., the kid with history's biggest Afro.
Last night's flashback episode, when the gang thought that Y2K had ended the world.
Lori F. is owned by:
Sadie, the four-legged dog
Martin, the three-legged cat
Paul, the two-legged husband