I'm sorry but from my experience and what our vet said the Ear mites are pretty much permanent, a chronic disorder because of the shape of the ear canal it's more susceptible, but it's not so bad since they're manageable with ear drops... you just have to continue with that treatment. you notice the ear perk up right afterwards, right? If not you might try another solution, but my cat had this trouble all his life and we just used whatever the vet prescribed as needed, and it worked directly after administration but of course only temporary