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Help! Vestibular or neuromuscular disorder?

5.2K views 4 replies 4 participants last post by  drjean  
#1 ·
Hello everyone,

I write out of desperation because my cat is very ill. :cry: I'm hoping that someone on this board might have some insight into the source of her condition (she has defied diagnosis so far)

Here is her medical history:

[1] ~4 years ago she manifested signs consistent with idiopathic feline vestibular disease (rapid onset, head-tilt, inability to walk straight, and general listlessness). Thankfully, the condition improved dramatically within 3 days.

[2] She seemed quite healthy for some time afterwards, though her weight ballooned to 18 lbs over the next several years.

[3] Concerned about her weight, we switched her diet to R/D and she lost weight rapidly... too rapidly probably. She dropped from 18 to 13 lbs within 6 months.

[4] ~2 weeks ago she had a recurrence of the apparent vestibular disease symptoms she suffered 4 years ago. She barely drank/ate food for several days. Blood tests showed nothing unusual except for a slightly elevated glucose level, but urinalysis revealed no glucose passed in the urine. This latter result, coupled with the absence of typical behavioral indicators of diabetes, suggest that the elevated glucose may be simply due to stress. The urinalysis also revealed no sign of bacterial infection.

[5] She seemed to recover from the apparent vestibular episode after 3-4 days and resume eating/drinking. However, after a few more days she suddenly had developed a severe limp, as if her back rear leg were injured. We took her in to be examined, and there were no obvious signs of injury, so we chose to wait and hope for improvement.

Her limp seemed to improve over the next several days, but then she suddenly relapsed into the vestibular disease symptoms we had observed before. She refused to drink/eat and became severely dehydrated. We gave her IV fluids for 24 hours, and afterwards we were terribly alarmed to find that she could barely walk at all.

Both her hind limbs seem to be either weak or unresponsive, though she seems fairly mentally alert, and does not have the severe head tilt that she suffered earlier. Our veterinarian is unable to reach a diagnosis, and we fear that she will die unless we can discover the root cause of her problem and treat her so that she will drink/eat once again.

[6] The only other possibly relevant information is that an exploratory x-ray revealed ~12 bladder stones (though none appeared to be obstructing any passages).

Many thanks for reading... any advice on how to proceed with treatments or diagnostics would be greatly appreciated.
 
#2 ·
Welcome Commander, and I'm sorry it is under such serious conditions.
I have only one idea for you to look into, and that is the fast onset of her back legs not working. Unfortunately I cannot recall the name of the problem, but it is where the kitty gets a blood clot and it restricts flow to the back and hind legs. Thrombosis something? Something thrombosis?

We just lost a kitty who had an idiopathic degeneration of his back and hind legs. It progressed visually and steadily over Reilly's last 3 years, though we had always thought him a clutzy cat for the first 4 years we had him. Reilly was only 7 years old when he passed away this past summer. Anyhow, he went from hesitating with every step of his hind legs, to running 'sideways' when his spine would bend to the side, to taking 10 steps before he'd tilt and sit down suddenly, to being able to only take 2-3 steps before the sit down and then to barely being able to stand/walk at all, unless we pulled up on his tail to keep his spine level. His last months he spent scooting around on his hip and pulling himself along the carpet with his claws.
He was happy/healthy/playful and not in pain. He was having difficulty with elimination and I took steps to clean and keep him comfortable and accomodate him. His last days, he began to lose the activity of his colon and was becoming constipated and the meds from the vet stopped working so we had to say goodbye.
Vet finally found a reference for his symptoms and in discussion with her peers at a conference, it was thought that he had cancer of his spinal column that debilitated him more and more as it progressed. She said that even if we knew what this was when I first brought him in, the outcome would have been the same as there is no treatment to halt or slow the progression of the disease.

Anyhow, I guess what I really want to tell you, is it is great to love your kitty and wonderful to do all you can for the kitty. Sometimes, it is also okay (when it is the only thing left to do) to be able to release your kitty from their infirm body.
I am hoping that you and your vet(s) will be able to discover what is wrong and be able to correct it. I know hard it is to have to admit defeat and let go. It makes you feel like you failed the kitty. BUT, if you love your kitty, and the kitty knows you have loved it, it is NEVER a failure.
Best of luck and do keep us posted.
Heidi
 
#3 ·
I'm so sorry your kitty is so sick. I had thought blood clot as well to explain the most recent symptoms, but this condition is very very painful, it would be very obvious that she was hurting if this was what was going on. Does she seem to be in pain?

My next thought is a slow growing brain tumor. Unfortunatly, the only way to confirm this would be an MRI or something similar. Brain tumors are strange entities. They can appear overnight. Stay the same size for years, and then, inexplicably, start growing and causing problems. Spinal tumors are the same way. Since your cat is a fully vaccinated indoor pet, there is no real reason to suspect something viral, and since the xrays don't reveal a traumatic injury, that really leaves you with tumor.

Of course, there is no way for me or anyone online to know for sure, because we can't see your kitty or run any tests.

Whatever the outcome, I will keep you and your kitty in my prayers.
 
#4 ·
Thank you both for the replies and support. I will definitely raise the possibility of thrombus or tumor with my vet tomorrow morning. I read a bit more on thrombosis and a "saddle thrombus" would indeed cause rapid onset of hind limb paralysis, but my kitty does not have the telltale blue paw pads or weak pulse.

While her condition is grave, we still hold on to a bit of hope because she looked terribly ill four years ago during her first bout of vestibular symptoms and made a full recovery. However, the symptoms are certainly worse now... :cry:
 
#5 ·
Even though the urine is clear, diabetes can cause hind limb weakness because of nerve degeneration. Cats can get "transient" diabetes that comes and goes; perhaps on the day she was tested, it was in a dormant phase. Or, perhaps the bladder stones are compressing the local nerves or even nerve roots as they exit the spinal cord. It's hard to say without seeing the cat, so I'm just throwing out a few wild guesses just to get some ideas out there.

If she is still eating dry food, you might want to try a good canned food. Dry r/d isn't a great long-term diet; is a likely cause of bladder stones; and a deficiency associated with it might be another avenue to explore.