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She's a survivor

1.1K views 17 replies 6 participants last post by  CrazyCatWriter  
#1 ·
Okay, this is gonna be a long thread so please bear with me. I was a member a long, long time ago and just rejoined.

In mid-November, our eight year old cat Bishop passed away quite suddenly from a heart attack. He had no symptoms anything was wrong, no murmur, was eating, drinking, and making merry literally minutes before it happened. Needless to say my wife and I were quite traumatized over it.

Only a couple of days later we noticed our cat Ripley had lost weight. Ripley is a black rescue cat, nine years old. She's always been extremely lean and tiny, and we had taken her to the vet prior to make sure she didn't have diabetes or some thyroid condition making her so small, and she was cleared. But she seemed to go from her normal, slender self to notably bony overnight.

I asked my wife if she'd noticed her eating lately (our cats, we now have four after Bishop's passing, have always been basically free graze and self-regulated eaters) and she hadn't. She had been drinking water and taking her treats, so that day (Saturday if I remember right) I made a vet appointment for Friday.

Monday she stopped eating altogether, wouldn't even take treats, so Tuesday we took her in to the emergency vet. Tests showed her liver values through the roof (ACT over 1000), and she had an ultrasound which showed quite a few gallstones, but none appeared obstructive. I'm condensing a lot down because...it's a lot of in and out of the vet and such.

She was transferred to an internal medicine specialist, more tests done, hospitalized for four days on a feeding tube, anitbiotics, various medications to thin her bile, etc. yada yada. Options discussed, etc. Eventually we had an e-tube placed and we had her home for feedings and medications and she was doing better.

Then, after a checkup, she had still lost a little weight after having her etube put in (she didn't really, she'd lost more weight in the day before the tube was placed but after her last weighing, and was gaining it back but hadn't gained enough back to be more than her last weighing, if that makes sense). So the vet increased her etube feedings by five mils. That same day I increased her food, she started drooling and growled at me when I touched her (this is the sweetest cat in the world, she's never growled at me or anyone other than her brother when he tries to play and doesn't take no for an answer). I called the vet thinking she was obstructed and the vet suggested that it was probably the increased feeding was making her feel overfull and to back down to the other level again and slowly ramp it up by a mil or so at a feeding. This seemed to do the trick, the next day no more drooling.

A day or so later (it all blurs together) she started acting uncomfortable again and vomited all over the place. Another call to the vet, she added on a second, stronger anti-nausea med, and again that seemed to do the trick. Until about a day later when I noticed she was turning yellow.

We immediately went back to the vet and she was hospitalized again (ACT now over 1200 and bilirubin up. At some point she was hypercalcemic as well but I think that was before the e-tube was put in?)

Vet did another ultrasound, gallstones didn't appear to have moved or changed much and didn't seem to be blocking, so she wanted to do a liver biopsy. We agreed and just before the biopsy the vet called back and said she'd talked to the surgeon and he suggested removing her gallbladder at the same time to stop the vector for secondary infection and keep her from obstructing. He also mentioned he'd seen cases before of cats that didn't look obstructed but actually were. So we talked again and agreed to do the gall bladder removal at the same time.

She had the surgery Christmas day. Surgeon got in there, and lo and behold she's not only obstructed, she's obstructed in more than one place and has twice as many gallstones as they could see on ultrasound.

Immediately after we got her home she was acting and doing so much better. We had to put her in a onesie because she got her cone off straight away and would not leave it alone. We were still giving her medicines and feedings four times a day and cleaning/bandaging her e-tube site etc. but she improved every single day.

On New Years she started eating kibble again, just little mouthfuls here. On the 4th, she started going to the dish and eating on her own. Again, just mouthfuls. So we started weighing her food to determine how much she was eating and on the 5th we cut out two of the four tube feedings and reduced the remaining two depending on how much kibble she ate before them.

On the 13th she was eating enough kibble I cut it down to one tube feeding, and then on the 14th I stopped the tube feedings altogether.

Now here's where things have gone wrong. She's supposed to go in on Monday and have a final checkup and have her e-tube removed.

But one of the meds she was on was Mirataz, given in her ears, to stimulate her appetite. We alternated ears each night. About the 13th, the same time we cut her down to one tube feeding, we noticed her ears were really dry and the tips were beginning to flop, and the sides to curl in. We discovered this can be a side-effect of long term Mirataz use, so we stopped it immediately, cleaned up her ears, and put some vaseline on them. We did this for a couple days and now they are no longer dry but haven't really straightened up.

When I stopped the tube feedings I also stopped her anti-nausea meds (Ondansetron and Cerenia) and just kept her on her liver meds (denemarin). The vet had said prior to go ahead and switch the cerenia to every other day until it was gone, but I stopped them both when she was eating the kibble on her own, because she had shown no sign of nausea at all since her surgery. I think this was a mistake.

She was eating well on the 15th, including overnight on her own, but yesterday morning she didn't want to touch her kibble again. Yesterday in total she ate only four grams on her own. I supplemented with 38 mils of her tube feeds, and she ate two of her treats and that's it.

She also brought up a hairball yesterday (she's been grooming a lot since her onesie came off), and has been licking and acting nauseous again last night and this morning.

I gave her the cerenia again last night, and the ondansetron this morning, and I gave her a partial tube feeding (23 mils instead of a 'full' feeding of 48) after she refused to touch the kibble again (she did sniff it this time and seem interested, then backed away). I'm going to try again with the kibble around noon and do a tube feeding again if she doesn't eat, but has anyone else been through this?

Her liver biopsies came back fine- no sign of infection, cancer, etc. Her last blood test after her surgery showed that her liver values had dropped back down into the high normal range, and we are pretty sure her entire issue was the gallbladder, but now, on the cusp of having her tube out, she's not eating again.

We're obviously going to talk to the vet again about all this on Monday, but were we wrong to stop the anti-nausea meds? She can't stay on them, or the appetite stimulants, forever, but what could be causing this nausea? After so many tests I really don't think it could be something else other than the gallbladder which is causing all this, but how can we be sure?

Is it as simple as a irritation from a hairball after grooming so much? We really want to get her tube out, but we're terrified if we take it out she's going to stop eating again even with the meds, and we have to put it back in?

I'm not expecting anyone here to have the answers. As I said, we're going to discuss all this with the vet on Monday. It's just, it's been such a roller coaster with this girl for weeks and weeks. Every time she seems to be better and on the verge of full recovery, she relapses. Has anyone else dealt with continuing nausea and anorexia after gallbladder removal due to obstruction?

Part of the problem is she's always been SUCH a picky eater (she hates wet food, and even most treats. She refuses to touch her old kibble after this so we went through about a dozen different new kibbles to get one she'll actually eat now. She refuses everything people suggest to get her weight up: churu, hates it. Nutrical, no thank you.

The only treats she'll take are greenies and a bit of plain boiled chicken. Literally everything else is a nope. Wet food, flat nope. Before the feeding tube she did take a little babyfood so long as it was mixed in with the boiled chicken, but she had to be hand-fed it and after a few times it became a 'nope' too, and she refuses to touch it.

Also, it's been a bear to find out how many kcals she should be eating (are 'normal' for her). When she was eating just the kibble and had an appetite she ate between 104 and 132 kcal, and that's including her treats (6-8 greenies). The vet had her on between 43 and 48ml for her tube feedings four times a day, so about 170-192kcals, but that was to put weight back on her. She's still not to her full weight again but she's around 7.5-7.9 lbs. Her weight before all this began was 8.9 lbs.

It's so hard because I want to hold back on the tube feedings so she's hungry and eats her kibble, but we can't afford her slipping backward on her weight again. Yesterday, even with the supplemental tube feeding, she only took in 54kcal.

So I guess, any thoughts? Advice, if you've been in this spot before? Suggestions on a good kcal intake since the internet is entirely useless for figuring this out?

She's just been through so much, and we were sooo close to being on the other side of this :(
 
#4 ·
I appreciate that but I honestly don't remember. I'm not even sure what email address I used for it. It's been years and honestly I'm lucky if I remember what day of the week it is any more!

I'm kinda new here but Welcome back anyway, I'm Sorry that I can't help when it comes to all this vet stuff, but I do want to say that your girl is a real trooper to be able to go through all this stuff, I only hope for the best................
<3

So update from yesterday: I did call her vet and give her a heads up about what was going on.

I believe I figured out why she's still nauseous. I was looking over all her meds again yesterday and realized that the denamarin should not be crushed. I've been crushing it and giving it with her other meds through her e-tube. I looked up her old discharge instructions, certain I had seen on there that we were supposed to crush it, but sure enough it says 'give by mouth'.

So I think me crushing it and giving it to her has irritated her stomach, but when she was on the anti-nausea and anti-emetics they kept her from feeling sick from it. When I stopped those but kept crushing up the denamarin, the nausea was free to rise.

Last night was a struggle :( After discovering this, I gave her the other meds by her tube but we instead tried to give the denamarin orally. She seemed to swallow it, but shortly afterward (five minutes or so) began pacing and acting uncomfortable and nauseous. She kept going in and out of the trays, licking a lot. Then she started making a noise. I thought she was hissing at first but it could have been a kind of 'hrrrnh' noise as well, like when you try and clear your throat.

She got in a tray, then got out and immediately (no wretching or anything) coughed out the pill and a little bit of fluid. We think she didn't quite swallow it and it was stuck down her throat.

We didn't readminister it, she was acting too uncomfortable for us to want to try it. I went to bed and she laid on me for a minute then got down and started pacing again, licking and hopping in and out of the litter tray. She didn't try and dig or act like she was going, she'd just hope in, sniff around a moment, then hop out and pace again. She cried once or twice, which made me get out of bed to see if she was going to hurl, but she never vomited. I felt for her bladder (we had a kitty years ago who had a growth in his urethra which caused him to be unable to pee several times) just to be safe and it was empty. I sat on the floor and she'd come up to me and lift her tail or headbutt me but then go pacing off again licking.

She didn't puke, and eventually climbed back up into bed with me and snuggled a little before settling down by my legs and going to sleep. This morning she woke us up purring. I gave her the ondansetron in her tube with some water, and she acted uncomfortable as soon as it went in her stomach, trying to hide in the blanket and licking again. But soon she was snuggling and purring again, though she did drool a little.

We tried her with a little kibble an hour later but she only sniffed it and turned away. I'm going to try again around noon and if she doesn't take it give her a tube feeding.

I think we're going to not give her the denamarin at all until we see the vet on Monday.
 
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#6 ·
If all she will eat is kibble, she has probably been in a chronic state of dehydration throughout her life - hence the gall stones and blockages. It sounds like the etube is the only way she was getting adequate moisture and as soon as you backed off of that, she reverted.

Might she accept some wet food if you mix some kibble in with it?
 
#7 ·
I appreciate the thought, and its good advice!

However, dehydration isn't and has never been her problem. Despite only eating dry food, she has always been a big drinker, which is why we had the vet check that she wasn't diabetic. At every vet check we make sure she's not dehydrated. The first thing she did when we started to slack off on the tube feedings to get her hungry so she'd start eating her kibble again was go to the water dish. We see her drinking from the dish probably three or four times a day (and that's just what we see). And she has been peeing very well. Her kidney function is all good.

But I will bring that up with the vet tomorrow, just to be safe!

As for the accepting wet food if mixed with kibble, sadly no. We tried that several times over the years, especially after her first vet visit when she stopped eating. The best we could do is she would take some boiled chicken mixed with wet babyfood if it was hand-fed to her, and then after only a couple of times of that working refused it as well.
 
#10 ·
I just wanted to do a quick update about her vet visit yesterday.

She did lose a little weight (was 7.5 and is now 7.3) and we went over everything. They didn't want to restart the denamarin right now but they did restart her prednisolone. We got an oral version of the mirataz, got a baseline caloric intake she needs to meet each day (and if she doesn't, I'll give her a tube feeding to make up the calories). She looked great, healing up great, doesn't seem to have any pain.

They decided to restart her prednisolone because her ALT is up again and as she was on the prednisolone when they took the liver biopsies it may have been masking some chronic inflammatory problem so they want her on it again with a recheck.

As for eating, yesterday her appetite came back with a vengeance. She ate 68g on her own which is the most she's done since this whole mess started, which is 244 kcal.

Last night, she housed another 18g. I was certain she wasn't going to meet her minimum calorie goal yesterday and she'd need supplemental tube feedings at least for a couple days before she got up there again, and she not only met it she blew it out of the water (and went 14kcal over the upper amount she should be getting normally). So methinks restarting her meds worked. If this keeps up she'll have her etube out in two weeks!
 
#16 ·
Appreciate the suggestion, but right now I don't think calories are her problem! Yesterday, she put away 323 kcal. We're starting to look under the bed and other furniture near where she eats to make sure she's not stashing some of the kibble away.

I didn't give her the mirataz this morning to see what her appetite does. I'm actually worried now she's going to gorge herself sick, though she seems to walk away from it before she gets overly full.
 
#18 ·
Quick update: she's still doing very well. She's off the mirtazapine as of the last four or five days and still eating well over 200 kcal every day. We've reduced her ondansatron by a quarter of a dose and we're stopping her cerenia tonight to see if her nausea comes back. Right now the plan is to get her etube out on Tuesday! So fingers crossed.
 
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